Thrombotic Microangiopathy in a Transplant Recipient
نویسندگان
چکیده
منابع مشابه
Progressive multifocal cerebral infarction in a young kidney transplant recipient due to thrombotic microangiopathy
BACKGROUND Renal transplant recipients frequently experience neurological complications. Whereas ischemic stroke, cerebral haemorrhage or hypertensive encephalopathy often result from vascular alterations prior to transplantation, other cerebral diseases like CNS infections, primary brain tumors and drug induced neurotoxicity may develop as consequences of the required post-transplant immunosup...
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Vascular endothelium is damaged by toxic agents during the preparation regimen for stem cell transplantation. Microthrombi develop in small arterioles and capillaries and cause partial obstruction. Erithrocytes are subjected to mechanical trauma, and as a result, to hemolysis and fragmentation. Patients have clinical symptoms similar to thrombotic thrombocytopenic purpura (TTP) and Hemolytic Ur...
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Thrombotic microangiopathy (TMA), not an uncommon but potentially serious complication of transplantation, occurs in 3–15% of renal transplant recipients [1,2]. De novo post-transplant TMA is mostly due to calcineurin inhibitor toxicity. Histologically, TMA is characterized by glomerular endocapillary damage with subendothelial accumulation of amorphous material. Narrowing or occlusion of capil...
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results during 2014, we encountered five patients with suspicious amr or tma at our kidney transplant center. renal biopsy was performed for two of them, suggesting amr for one patient and tma for another patient. all patients were treated with plasmapheresis plus ivig. in this center, as a routine practice, the cumulative dose of 2 g/kg of ivig was divided to 300 - 400 mg/kg after each plasmap...
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Hepatitis B virus (HBV) presents a risk to patients and staff in renal units. To minimise viral transmission, there are international and UK guidelines recommending HBV immunisation for patients commencing renal replacement therapy (RRT) and HBV surveillance in kidney transplant recipients. We report the case of a 56-year-old male who was immunised against HBV before starting haemodialysis. He ...
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ژورنال
عنوان ژورنال: Clinical Journal of the American Society of Nephrology
سال: 2018
ISSN: 1555-9041,1555-905X
DOI: 10.2215/cjn.00020118